The Kisii County Government Ministers (CECs) are listed below. Governor Simba Arati, who was elected on the ODM platform on August 12, 2022, is in charge of Kisii County.
The ten County Executive Committee members and cabinet secretaries that make up Kisii County’s government system are given below.
| Ministry | Minister (CEC) | |
| 1 | Medical Services, Public Health & Sanitation | Leah Ogega |
| 2 | Finance, Economic Planning & ICT services | Kennedy Abincha |
| 3 | Land, Physical Planning, Housing & Urban Development | Grace Nyarangi |
| 4 | Infrastructure, Energy and Public Works | Cyrus Nyabicha |
| 5 | Education, Technical Training, Innovation, & Social Sciences | Elijah Obwori |
| 6 | Agriculture, Fisheries, Livestock Development & Fisheries | Beatrice Mong’ina Doyle |
| 7 | Trade, Tourism & Marketing | Alfred Ndemo Ongera |
| 8 | Public Service, County Administration & Participatory Development | Daniel Nyakundi |
| 9 | Sports, Culture & Arts | Eric Miyienda |
| 10 | Water & Environment | Ronald Nyakweba |
