If you want to create a new keyboard shortcut, navigate down to App Shortcuts, click the plus, select the application you want (or select All Applications), and type the menu title of your shortcut along with the keys you want to use. Then click Add. Take note, in order for the shortcut to work you will need to type in the exact syntax of the menu title; that includes capitalization, spaces, and punctuation. To change an existing shortcut you can select the one you want to change, click on the key combination, and then type the new keys you want to use.